![]() In addition, physiological connectivity developed between the ipsilateral hemisphere and the paralyzed hand. This procedure was found to be associated with a greater improvement in function and reduction of spasticity than rehabilitation alone over a period of 12 months. found that the paralyzed upper limb can be functionally connected to the contralesional (ipsilateral) hemisphere by transferring a cervical spinal nerve from the nonparalyzed side to the paralyzed side. Through a number of studies and clinical observations, Xu et al. However, only approximately 2% of motor nerve fibers in the upper and lower limbs do not cross and are innervated by the ipsilateral cerebral hemisphere, which heavily limits the compensatory effect of the contralesional brain. The recovery of patients with severe stroke is largely dependent on the compensatory mechanisms of unaffected hemisphere. These methods either have side effects, limited effect of muscle tone, or have little effect on the function of paralyzed upper limb. Additionally, stretching, fitting of splints, muscle strengthening and movement training are commonly used non-pharmacologic treatments. ![]() Some pharmacologic treatment options can be used to treat spastic paralysis. It has been estimated that 30–60% of stroke patients are not able to voluntarily control their paretic hand, as most of them have shown a flexor spasm pattern. Spastic paralysis is a common consequence of stroke and is an important contributor to long-term disability.
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